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Quick detail
Product name: Finasteride
CAS: 98319-26-7
Appearance: White or white crystalline powder
Grade: Pharmaceutical grade
Package: Disguised package ; Foil bag
Delivery date: 3-5 work days
Chemical Formula: C23H36N2O2
Description: White or white crystalline powder
Specification: USP
Packing: 1kg/tin
Min. Order quantity: 10g
Payment: Western Union, MoneyGram, T/T, bitcoin
Shipment: EMS, DHL, FedEx
Powder: Yes
Certification: GMP, ISO 9001, USP, BP
State: Solid
Shipping Time: Process Order Within 12hours
Trademark: Pharmlab
Finasteride Specifications COA
Test Items | Specification | Test Results | |
Description | White or off-white crystalline powder | Off-white crystalline powder | |
Specific rotation | -56°~-60° | -58.2° | |
Identification | IR | Matches with working standard | Complies |
HPLC | |||
Solubility | Freely soluble in chloroform and in alcohol; Very slightly soluble in water | Conform | |
Heavy metals | ≤10ppm | <10ppm | |
Water | ≤0.3% | 0.22% | |
Residue on ignition | ≤0.1% | 0.05% | |
Relative material | Maximum impurities≤0.5% | 0.36% | |
Total impurities≤1.0% | 0.52% | ||
Assay | 98.5~101.0% | 99.68% | |
Conclusion | The specification conform with Enterprise standard |
Product description
Finasteride is a synthetic 4-aza-steroidal compound and is a specific inhibitor of steroid II5α-reductase, which is an intracellular enzyme that converts androgen testosterone to 5α-dihydrotestosterone (DHT).
Finasteride is 4-aza-androst-1-ene-17-carboxamide, N- (1,1-dimethylethyl) -3-oxo (5A, 17A) -. The empirical formula for finasteride is C23H36N2O2 with a molecular weight of 372.55.
Finasteride is a white crystalline powder with a melting point close to 250 ° C. It is soluble in chloroform and lower alcohol solvents, but is almost insoluble in water. The finasteride tablets for oral administration are film coated tablets containing 5 mg of finasteride and the following inactive ingredients: aqueous lactose, microcrystalline cellulose, pregelatinized starch, sodium hydroxyethyl starch, hydroxypropyl Cellulose, LF, hydroxypropylmethylcellulose, titanium dioxide, magnesium stearate, talc, docusate sodium, FD & C blue 2 aluminum lake and yellow iron oxide.
Finasteride: Proscar; prostate powder; bald treatment treatment of hair loss pharmaceutical raw materials
Finasteride is a popular antiandrogenic drug produced by Merck, most commonly known as Proscar or Propecia. Based on the progesterone skeleton, finasteride belongs to a class of drugs known as 5α-reductase inhibitors and is therefore used for the rotation therapy around the type 2 5-AR gene.
This is important for performance enhancers because DHT-based anabolic steroids have a specific side effect that may occur, which can be largely remedied by the use of 5-AR inhibitors such as finasteride.
As a type 2 5-AR inhibitor, finasteride is designed for the treatment of hair loss, benign prostatic hyperplasia and prostate cancer.
Finasteride is very common in people who add synthetic metabolic steroids but are still worried about hair loss, but before you consider the use of finasteride, you need to understand important things. As an androgen inhibitor, finasteride can strictly inhibit the cycle of harvesting, seriously, on this basis, is not strongly recommended in circulating hair preservation.
Propecia is used to treat male male alopecia (androgenic alopecia). Locally (on the scalp itself), has a certain effect in reducing further hair loss. Combined with Nizoral and spironolactone (its taste is very bad), can actually be moderately reversed.
For the treatment of prostate disease. Clinical studies have shown that the use of finasteride 1 mg / day, continuous oral 3 months or slightly longer can have hair growth, continuous treatment after 1 year hair growth rate of 48%, and can continue to fall off, taking hair tissue 2 years hair The growth rate of 66% to 83%.
Product indications and usage
Finasteride is used to treat benign prostatic hyperplasia in men with symptomatic benign prostatic hyperplasia (BPH): improving symptoms - reducing the risk of acute urinary retention - reducing the risk of surgery, including transurethral resection of prostate (TURP) and prostate cut. The finasteride administered in combination with the opioid inhibitor doxazosin was indicated to reduce the risk of symptomatic progression of BPH (the AUA symptom score was confirmed to be an increase in e4 point).
Product effect
(1) benign prostatic hyperplasia
The physician uses finasteride to treat BPH, informally known as the enlarged prostate. Finasteride can improve symptoms associated with BPH, such as dysuria, get up at night, urination, urination began to hesitate, reduced urinary flow.
(2) male type baldness
Finasteride is used to treat male male hair loss (androgenic alopecia). Treatment 6 months after treatment can reduce the hair loss of 30% improvement, as long as the medication, the effect will continue.
(3) non-label use
Finasteride is sometimes used in hormone replacement therapy for male to female transsexuals because of its antiandrogenic properties in combination with estrogen forms. However, there have been few studies of finasteride for this purpose, and evidence of efficacy is limited.
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