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Product Name: Propitocaine hydrochloride
Other name: Propitocaine HCl; Prilocaine HCl
Synonyms: Prilocaine hydrochloride; 2-(Propylamino)-o-propionotoluidide hydrochloride; Alpha-propylamino-2'-methylpropionanilide hydrochloride; Citanest; N-(2-Methylphenyl)-2-(propylamino)-propanamide hydrochloride; N-(a-propylaminopropionyl)-o-toluidine hydrochloride; Prilocaine hydrochloride; Xylonest; ; N-(2-methylphenyl)-N~2~-propylalaninamide hydrochloride (1: 1); Propitocaine HCl
CAS No.: 1786-81-8
EINEC No.: 217-244-0
M. F.: C13H21ClN2O
M. W.: 256.7716
Steam pressure: 2.05E-05mmHg at 25 ° C
Catalog: Antibacterial ;local anesthetics
Appearance: White crystalline odorless powder ,taste slightly bitter sour .
Usage: Local anesthetics, long duration, lower toxicity, chemicals that are also small Suitable for epidural anesthesia, block anesthesia and infiltration anesthesia, etc.

Propitocaine HCl Description

Propitocaine hydrochloride is a local anesthetic of the amino amide type first prepared by Claes Tegner and Nils Lö Fgren. In its injectable form, it is often used in dentistry. It is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/prilocaine or EMLA), for treatment of conditions like paresthesia. As it has low cardiac toxicity, it is commonly used forintravenous regional anaesthesia.

In some patients, a metabolite of prilocaine may cause the unusual side effect of methemoglobinemia,which may be treated with methylene blue.

Local anesthetic is a substance that causes loss of sensation only to the area to which it is applied without affecting consciousness. Most local anesthetics structures have amino-ester or an amino-amide group which are linked to hydrophilic (secondary or tertiary amine) and to hydrophobic group (aromatics) on the other sid. The ester can be hydrolysed in plasma by the enzyme pseudocholinesterase into para-aminobenzoic acid. Amide is stable for longer acting and more systemic distribution. Ester types include Procaine (Novocain) Chloroprocaine (Nesacaine), Cocaine, Tetracaine (Pontocaine), Benzocaine,Tetracaine. Amide types include Lidocaine (Xylocaine), Mepivacaine(Carbocaine), Prilocaine (Citanest),Bupivacaine (Marcaine), Etidocaine (Duranest).

Propitocaine hydrochloride Specification

Propitocaine hydrochloride Application :

Prilocaine is a local anesthetic of the amino amide type. Prilocaine is often used in dentistry. Prilocaine is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/pril ocaine or EMLA), for treatment of conditions like paresthesia.

Local anesthetic is a substance that causes loss of sensation only to the area to which it is applied without affecting consciousness. Most local anesthetics structures have amino-ester or an amino-amide group which are linked to hydrophilic (secondary or tertiary amine).

The ester can be hydrolysed in plasma by the enzyme pseudocholinesterase into PARA-aminobenzoic acid. Amide is stable for longer acting and more systemic distribution. Ester types include Procaine (Novocain), Chloroprocaine (Nesacaine), Tetracaine (Pontocaine), Benzocaine, Tetracaine. Amide types include Lidocaine (Xylocaine), Mepivacaine(Carbocaine), Prilocaine (Citanest), Bupivacaine (Marcaine), Etidocaine (Duranest).

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