1. Quick details

Ipamorelinis a fascinating new muscle building discovery that is getting a lot of attention in the bodybuilding world. Like the GHRP-6 peptide (growth hormone releasing hexapeptide), it is a synthetic peptide that has powerful Growth Hormone releasing properties. And these GH releasing properties are what is of interest to athletes and bodybuilders since they can make a tremendous difference in the amount of muscle you can grow and how quickly you burn fat.

Product name :Ipamorelin
Unit Size :2 mg/vial
Unit Quantity :1 Vial
CAS: 170851-70-4
Formula: C38H49N9O5
MW:711.853
purity:99%
Appearance: White Lyophilized Powder
Grade : Pharmaceutical Grade
Storage Lyophilized Ipamorelin is stable at room temperature for 90 days,however it should be stored in a freezer below -8C for any extended period of time. After reconstituting Ipamorelin should be refrigerated at temperatures not to exceed 36 F.

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2. Description & Application 

Ipamorelin is an interesting peptide taken 300mcg twice daily or you could lower the dose for 3 times daily, side effects are head rushs, I would recommend taking this 30 minutes before workout ,with gear, Ipamorelin is a new and potent synthetic pentapeptide which has distinct and specific growth hormone releasing properties. With the objective of investigating the effects on longitudinal bone growth rate , body weight , and growth hormone release, Ipamorelin in different doses (0, 18, 90 and 450 μg/day) was injected three times daily for 15 days to test subjects, After intravital Tetracycline labelling on days 0, 6, and 13, LGR was determined by measuring the distance between the respective fluorescent bands in the proximal tibia metaphysis. Ipamorelin dose-dependently increased LGR from 42 μm/day in the vehicle group to 44, 50, and 52 μm/day in the treatment groups .

There was also a pronounced and dose-dependent effect on body weight gain. The treatment did not affect total IGF-I levels, or serum markers of bone formation and resorption. The number of tartrate-resistant acid phosphatase-positive multinuclear cells in the metaphysis of the tibia did not change significantly with treatment.

3. Function 

Ipamorelin can be said that it is similar to GHRP-6 in the way of increasing ghrelin and gastric motility, as well as, targeting a selective GH pulse. Though, the hunger sides on Ipamorelin are virtually zero. This makes it a much more versatile peptide for before-bed time dosing. Unlike GHRP-6 and GHRP-2, Ipamorelin was shown at high doses to have almost no direct impact on cortisol or prolactin production. This means users can dose higher and with greater frequency without having to be worried about cortisol and acetylcholine blood plasma levels being elevated. In short, it may be the mildest GHRP, but it is in no way the weakest. In fact, as a GHRP, it has shown to be one of longest lasting, and, at higher doses, the most potent. Ipamorelin’s function is a slow building one that is much more like the body’s natural growth hormone (GH) release. This makes it the healthiest choice in the bunch!

4. How to use Ipamorelin ?

After an athlete administers Ipamorelin, a selective pulse is sent that stimulates the hypothalamus/pituitary to release GH. This pulse can endure for approximately three hours after injection. Once the GH pulse is sent, the cells go directly to the muscle to support development while staying clear of any possible bone or cartilage growth. This is good for Ipamorelin users, as long term usage will effect lean body muscle growth without the possibility of experiencing any bone or cartilage deformities. The same cannot be said for synthetic HGH users, who experience pronounced side effect in swelling joints and even in some cases Carpel Tunnel. Ipamorelin will increase cell synthesis, elevate secretion levels of insulin from pancreatic tissue, and increase ghrelin in the stomach – which helps release GH and control hunger. All of these functions work to promote fat loss, shuttling of nutrients, and building clean muscle mass.

5. Dose

Ipamorelin, like other peptides, comes as a freeze dried powder that is very delicate. You can store it in the refrigerator or at room temperature before reconstituting. Once reconstituted with bacteriostatic water, the vials must be stored in a cool dry place like your refrigerator. Insulin syringes are the best way to administer it, usually via subcutaneous injection.

Of course, using iPamorelin with a GHRH like CJC w/out DAC will give the user the biggest increase in GH and IGF-1 as GHRP’s and GHRH’s work together synergetically. The average dosing for Ipamorelin is 200-300mcg two to three times daily. Twelve week cycles are quite normal and PCT would be very minimal – mini-pct is fine. If prolactin issues ever arise, there are products that help reduce prolactin and estrogen-like symptoms. These include aromatase inhibitors (Aromasin, Arimidex, Letrozole), and anti-prolactin aids like Dostinex (Cabergoline).

 Specification

7. Ipamorelin vs. GHRP

Ipamorelin is a 3rd generation GHRP behind GHRP-6 and GHRP-2

Ipamorelin has very similar characteristics of GHRP-2: does not have ghrelin's lipogenic properties and does not promote hunger. Ipamorelin acts synergistically when applied during a Growth Hormone Releasing Hormone (GHRH) pulse or when it is administered along with a GHRH or an analog such as Sermorelin or Modified GRF 1-29 (growth releasing factor, aminos 1-29). The synergy comes both due to the suppression of somatostatin and the fact that ipamorelin increases growth hormone release per-somatotrope, while GHRH increases the number of somatotropes releasing GH. On the other hand, Ipamorelin is similar to GHRP-6 because they both release growth hormone at a very similar strength minus the side effects that of GHRP-6. Both GHRP-6 and GHRP-2 cause a release and an increase in cortisol and prolactin levels, however Ipamorelin only selectively releases growth hormone at any dose. Ipamorelin shares similar functionality to Hexarelin and compared to other peptides, it is a much more stable form of ghrelin and has longer half-life periods of at least two hours long and causes secondary effect by making neurons to become excited.

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