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Quick detail
Product name: Pentadecapeptide BPC 157
Other name: BPC 157
Appearance: white lyophilized powder
purity: 99%
Trademark: Pharmlab
Original: China
Grade: Pharmaceutical grade
Package: Disguised package ; Foil bag
Delivery date: 3-5 work days
Certificate: ISO 9001, USP,GMP
Payment: Western Union, MoneyGram, T/T, bitcoin
Shipping: EMS,HKEMS,EUB,ETK,FEDEX,DHL,UPS,Aramex,ETC
Suitable for: Adult
Molecular Fomular: C17h11n5
Molecular Weight: 285.3
Single Impurity(HPLC):2mg/vial
Amino Acid Composition:10% of theoretical
Storage: Although stable at room temperature for 3 months, the freeze-dried peptide should be stored below -18 ° C and stored below -18 ° C. After reconstituting the peptide, it should be stored at 4 ° C for 2-21 days for later use at -18 ° C.
COA
Test Items | Specification | Results |
Description | white lyophilized powder | white lyophilized powder |
Melting Point | 191.0~193.0ºC | 192ºC |
Loss of drying | ≤1.0% | 0.5% |
Heavy Metal | ≤20ppm | 15ppm |
TLC | Only one spot | Only one spot |
Assay | ≥99.5% | 99.91% |
Conclusion | It complies with the USP 32. |
Product description
BPC 157 (Body Protection Compound-157) is a 15-amino acid pentapeptide. The amino acid sequence in BPC 157 is similar to a portion of the human BPC amino acid sequence. Gastric acid found in human BPC. Experiments show that BPC157 can enhance wound healing, including tendon wounds, such as rat transected Achilles tendon. The aim of this study was to investigate the possible mechanisms by which BPC 157 was used to accelerate the healing process of injured tendons. The study used two sets of tendon explants, one of which was cultured in BPC157-containing medium and the other was cultured in a medium lacking BPC 157.
In addition, FITC-phalloidin staining demonstrated that BPC157 induced F-actin formation in fibroblasts. Similarly, Western blot analysis was able to detect the production and activation of pudding proteins and FAK proteins. Western blot analysis also showed that BPC157 increased the phosphorylation of puerarin and FAK protein without affecting the amount produced.
FITC-phalloidin staining demonstrated that BPC157 induced F-actin formation in fibroblasts. Similarly, Western blot analysis was able to detect the production and activation of pudding proteins and FAK proteins. Western blot analysis also showed that BPC157 increased the phosphorylation of puerarin and FAK protein without affecting the amount produced.
Product application
BPC 157 has a strong antiinflammatory activity in acute and chronic inflammatory models and may be an important treatment for the treatment of inflammatory bowel disease. BPC 157 shows accelerated wound healing and has significant angiogenesis. But also significantly promote the healing of rat fractures, showing osteogenesis, significantly improve the healing of segmental bone defects.BPC 157 accelerated transection rat Achilles tendon and transverse rat quadriceps muscle healing, significantly accelerated the tendon The growth of explants. The proliferation of Achilles tendon myofibroblasts derived from cultured tendon fibroblasts by MTT was not directly affected by BPC 157.
Bpc 157 working principle
BPC 157 has a strong antiinflammatory activity in acute and chronic inflammatory models. In fact, the preliminary results of clinical trials suggest that BPC 157 may be an important treatment for the treatment of inflammatory bowel disease. BPC 157 showed accelerated wound healing and had a significant angiogenesis effect. In addition, it significantly promotes rat fracture healing. The peptide also exhibits a significant improvement in the osteogenesis of segmental bone defects. BPC 157 accelerates the healing of the rat quadriceps of the Achilles tendon and transected rats.
FITC-phalloidin staining demonstrated that BPC157 induced F-actin formation in fibroblasts. Similarly, Western blot analysis was able to detect the production and activation of pudding proteins and FAK proteins. Western blot analysis also showed that BPC157 increased the phosphorylation of puerarin and FAK protein without affecting the amount produced.
Bpc 157 Advantages
BPC 157 has been shown in rat studies to cure damaged quadriceps muscles, isolated Achilles tendon, damaged / crushed muscles
muscle tear quickly recovered
tendon bone healing
increase ligament healing
organs have a variety of protective effects
Human trials indicate healing and prevention of gastric ulcer
No adverse reactions were seen in human trials.
BPC-157 effect
The main features of healing are granulation tissue, angiogenesis and collagen production. BPC-157 contributes to angiogenesis. Angiogenesis (vascular) formation (formation) is the formation of blood vessels. No, it's serious about this fool. Take any two words that they are out of order in Greek and / or Latin, and you get medical terminology.
BPC-157 works by regulating vascular endothelial growth factor (VEGF), a factor that causes capillaries to grow into new areas to carry blood and nutrients. How this happens through blood flow therapy. This occurs only in the actual tendon and muscle tissue, and cell culture of BPC-157 does not affect VEGF or healing.
BPC 157 Benifits
BPC 157 has been shown in rat studies to cure damaged quadriceps muscles, isolated Achilles tendon, damaged / shattered muscles
Muscle tearing rapid recovery
Muscle healing
Increased ligament healing
In the organ has a variety of protective effects
Human trials have proven to cure and prevent gastric ulcers
No adverse reactions were seen in human trials.
BPC 157 dose
The results were observed by oral, peritoneal and local injection. The results of the rats were 10 μg / kg. This means that oral or injection does not make any difference, only a little bit of this healing becomes easier.
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